Wegovy Oral Pill

Price range: £99.00 through £199.00

Wegovy® tablets are a once-daily oral weight loss treatment containing semaglutide. Now MHRA-approved for weight management in the UK, they offer a convenient, needle-free alternative to weekly weight loss injections.

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About Wegovy® Tablets

Wegovy® (semaglutide) is a prescription-only weight loss treatment developed by Novo Nordisk. Until recently, semaglutide was only available as a weekly injection. The tablet form offers the same active ingredient in a once-daily pill, making it a practical option for adults who prefer to avoid injections.

Semaglutide works by mimicking a naturally occurring hormone called GLP-1 (glucagon-like peptide-1). This hormone is released after eating and plays a key role in regulating appetite and blood sugar levels. By activating GLP-1 receptors in the brain, Wegovy® helps reduce hunger, increase feelings of fullness, and lower overall calorie intake.

Wegovy® tablets are intended to be used alongside a reduced-calorie diet and increased physical activity as part of a structured weight management programme. They are prescribed where clinically appropriate following a full medical assessment.

Wegovy® tablets have been approved by the MHRA for weight loss in the UK. They are currently only available via private prescription.

Directions

  • Take one tablet once daily, every day at the same time
  • Take it first thing in the morning on an empty stomach, before any food, drink, or other medication
  • Swallow the tablet whole with no more than 120 ml (half a cup) of plain water only
  • Do not crush, split, or chew the tablet
  • Wait at least 30 minutes before eating, drinking anything other than water, or taking any other oral medicines
  • Follow your prescriber’s dose schedule, which will gradually increase your dose over time to reduce the chance of side effects
  • If you miss a dose, skip it and take your next tablet the following morning as usual — do not take two doses on the same day

Side Effects

Like all medicines, Wegovy® tablets can cause side effects. Most are mild to moderate and tend to improve as your body adjusts to the medication, particularly during the dose-increase phase.

Common side effects include:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Stomach pain or discomfort
  • Indigestion or heartburn
  • Reduced appetite
  • Headache
  • Fatigue
  • Dizziness

Serious side effects — seek medical advice promptly if you experience:

  • Severe or persistent abdominal pain (which may indicate pancreatitis)
  • Symptoms of gallbladder problems such as pain in the upper right abdomen, fever, or jaundice
  • Signs of a serious allergic reaction such as swelling of the face, lips, or throat, difficulty breathing, or a rapid heartbeat
  • Changes in vision (which may indicate diabetic retinopathy complications)
  • Signs of low blood sugar if you are also taking insulin or sulfonylureas
  • Mood changes, depression, or thoughts of self-harm

This is not a full list of side effects. Read the patient information leaflet supplied with your medication and speak to your prescriber or pharmacist if you have any concerns.

Warnings

Wegovy® tablets are not suitable for everyone. Do not take this medication if you:

  • Have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have a known allergy or serious hypersensitivity to semaglutide or any ingredient in the tablet

Tell your prescriber before starting Wegovy® tablets if you:

  • Have or have previously had pancreatitis
  • Have gallbladder or kidney problems
  • Have diabetic eye disease (retinopathy)
  • Have a history of depression, anxiety, or suicidal thoughts
  • Are taking other medicines, particularly insulin, sulfonylureas, or any other oral medications (timing of administration may be affected)
  • Have any other serious medical conditions

Wegovy® tablets are a prescription-only medicine and are only prescribed following a full clinical assessment. Always follow the guidance of your prescriber and read the patient information leaflet before use.

Storage

  • Store at room temperature, below 30°C
  • Keep tablets in the original blister pack to protect them from moisture
  • Only remove a tablet from the blister immediately before taking it
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via wastewater or household waste — ask your pharmacist how to dispose of medicines you no longer need
  • Both the tablet and the injection contain the same active ingredient, semaglutide. The key difference is how they are taken: the injection is given once a week, while the tablet is taken once daily. The tablet must be taken on an empty stomach with strict timing rules to ensure it is absorbed properly.
  • Results vary between individuals. Wegovy® works gradually as your dose is increased over several months. Clinically meaningful weight loss is typically seen over a period of weeks to months when used consistently alongside diet and lifestyle changes.
  • Wegovy® tablets are used for chronic weight management in adults with obesity, or in adults who are overweight and have at least one weight-related health condition such as high blood pressure, high cholesterol, or type 2 diabetes. They are used alongside a reduced-calorie diet and increased physical activity.
  • There are no specific foods to avoid, but the tablet must be taken on a completely empty stomach. Food consumed before or too soon after taking the tablet significantly reduces how well the medication is absorbed. Follow the 30-minute waiting rule strictly.

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